systems consisting of lipid monolayers and adsorbed proteins are exposed to radicals. Repeated exposure to ROS/RNS will lead to fragmentation of the protein, and eventually of the model membrane. Fragmented [...] e destruction. For that end, macromolecules in a physiological solution will be exposed to ROS/RNS, adsorbed to a surface and imaged with AFM. The partial destruction of macromolecules will indicate pathways [...] polyunsaturated fatty acids in lipids. Also, both ROS and RNS may induce partial decomposition. We plan to investigate how these changes on a molecular level influence the ensemble. We use model membranes,
https://physik.uni-greifswald.de/dfg-forschungsverbuende/biox/1st-funding-period/projects-2014/project-b1-helm/